Mark and his sister Róisín are third generation pharmacists working in the family community pharmacy business on the Main Street in Ballyhaunis. Curley's Pharmacy was started in 1934 by their grandfather, Michael Curley in the same premises they run the pharmacy today from. Mark and Róisín's father Hugh joined the business in 1966 and continued to grow and develop the business his father had started. In 2010, Mark and Róisín took over running the business following the passing of their father Hugh. Róisín is also a member of the Board of the Totalhealth Pharmacy Group.